Endocrine Abstracts

Introduction and Aim: In our study, the frequency of exocrine pancreatic insufficiency, and its relationship with the duration of diabetes and the level of glycemic control and other complications of diabetes were investigated in patients with diabetes mellitus.Materials and Methods: This paper was supported by Manisa Celal Bayar University Scientific Research Projects Coordination Unit, Project Number 2021-086. A total of 249 diabetic patients, 21 with ...

Osteoprotogerin (OPG) and the receptor activators of nuclear factor-kβ (RANK) and nuclear factor-kβ ligand (RANKL) play an important role in bone metabolism. RANKL binds to RANK, which is expressed by osteoclasts, whereas OPG acts as its decoy receptor, blocking the RANK–RANKL interaction.The aim of our study was to evaluate bone turnover parameters (serum calcium, phosphorus, alkaline phosphatase, parathormone, osteocalcine, 24-...

Background: Hashimoto’s thyroiditis is a chronic autoimmune thyroiditis. It is the most common cause of primary hypothyroidism in adolescent period, via autoimmune thyroid tissue destruction and affecting 2% of the population. In this study we want to investigate the role of the cytokines such as IL-2, IL-12, TNF-α and IFN-γ in the pathogenesis of the disease and the changes of cytokine levels with the L-thyroxine treatment....

Thyroid hormones play an important role in bone metabolism. The potential action of prolonged levothyroxine therapy on bone mass reduction is stil a matter of debate.The aim of our one year prospective study was to elucidate whether longterm suppressive thyroid hormone therapy in patient with differentiated thyroid cancer (DTC) affects bone metabolism, osteoprotegerin (OPG) and soluble receptor activator of nuclear factor kβ ligand (sRANK-L) and is ...